dc.contributor.advisor | Henao Agudelo, Juan Sebastián | |
dc.contributor.author | Ducuara Villegas, Marcela | |
dc.contributor.author | Páez Castaño, Juan Manuel | |
dc.contributor.author | Tafur, Luisa Maria | |
dc.contributor.author | Salgado Tascón, Catalina | |
dc.contributor.other | Canizales Caicedo, Marco Tulio | |
dc.coverage.spatial | Tuluá, Valle del Cauca, Colombia | spa |
dc.date.accessioned | 2025-06-09T17:22:55Z | |
dc.date.available | 2025-06-09T17:22:55Z | |
dc.date.issued | 2025 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12993/4959 | |
dc.description | ilustraciones, gráficos, tablas | spa |
dc.description.abstract | El dengue es una enfermedad viral transmitida por mosquitos del género Aedes, que
representa un desafío significativo para la salud pública global, tanto por su alta carga de
morbilidad como por los elevados costos sanitarios y sociales que genera (1,2). En Colombia, la
incidencia del dengue ha mostrado un aumento sostenido en las últimas décadas, favorecido por
la circulación simultánea de múltiples serotipos y por condiciones ambientales propicias para la
proliferación del vector .
La presente revisión sistemática tiene como objetivo analizar la evidencia científica
disponible sobre los factores sociodemográficos, clínicos y epidemiológicos asociados a la
hospitalización por dengue en población pediátrica escolarizada. Esta revisión se orienta a
identificar patrones comunes y determinantes clave que inciden en la evolución clínica y en la
necesidad de atención hospitalaria, con el fin de aportar elementos relevantes para la práctica
clínica y la formulación de políticas en salud pública.
Se abordan variables como edad, sexo, nivel socioeconómico, antecedentes
epidemiológicos, sintomatología clínica y hallazgos paraclínicos, los cuales permiten caracterizar
los factores de riesgo asociados a una mayor severidad del dengue en menores entre los 6 y 17
años.
Los hallazgos de esta revisión permitirán orientar estrategias de promoción y prevención en salud,
enfocadas en reducir la tasa de hospitalización y prevenir complicaciones graves derivadas del
dengue, particularmente en poblaciones infantiles vulnerables. Asimismo, se espera contribuir al
fortalecimiento de las políticas públicas mediante la identificación de determinantes críticos para
la planificación de intervenciones eficaces, la optimización del uso de recursos sanitarios y el
control integrado del vector. | spa |
dc.description.tableofcontents | 1. RESUMEN /
ABSTRACT /
2. INTRODUCCIÓN /
3. PLANTEAMIENTO DEL PROBLEMA /
4. JUSTIFICACIÓN /
5. OBJETIVOS /
5.1. Objetivo general /
5.2. Objetivos específicos /
6. HIPÓTESIS /
7. METODOLOGÍA /
7.1. Estrategia de búsqueda /
7.2. Población y muestra /
8. RESULTADOS /
8.1. Proceso de selección de estudios según prisma /
8.2. Definición y agente etiológico /
8.3. Manifestaciones clínicas /
8.4. Diagnóstico /
8.5. Factores de riesgo /
8.6. Factores sociodemográficos /
8.7. Factores clínicos /
8.8. Factores epidemiológicos /
8.9. Epidemiología global /
8.10. Situación en Colombia /
8.11. Avances en investigación /
9. CONSIDERACIONES ÉTICAS /
10. DISCUSIÓN /
11. CONCLUSIONES /
12. RECOMENDACIONES /
13. APARTADO DE FINANCIAMIENTO /
14. REFERENCIAS | spa |
dc.format | PDF | spa |
dc.format.extent | 48 páginas | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | spa | spa |
dc.rights | Derechos reservados - Unidad Central del Valle del Cauca | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0 | * |
dc.title | Factores sociodemográficos, clínicos y epidemiológicos asociados a la hospitalización por dengue en población pediátrica | spa |
dc.type | bachelor thesis | spa |
dc.rights.license | Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) | * |
dcterms.audience | Público general | spa |
dcterms.audience | Docentes | spa |
dcterms.audience | Estudiantes | spa |
dcterms.audience | Investigadores | spa |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.publisher.program | Medicina | spa |
dc.publisher.faculty | Facultad de Ciencias de la Salud | spa |
dc.type.local | Tesis/Trabajo de grado - Monografía - Pregrado | spa |
dc.description.degreename | Medico | spa |
dc.description.degreelevel | Pregrado | spa |
dc.identifier.instname | Instname:Unidad Central del Valle del Cauca | spa |
dc.identifier.reponame | reponame:Repositorio Institucional Unidad Central del Valle del Cauca | spa |
dc.identifier.repourl | repourl:https://repositorio.uceva.edu.co/ | |
dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | spa |
dc.rights.local | Abierto (Texto Completo) | spa |
dc.type.content | Text | spa |
dc.type.driver | info:eu-repo/semantics/bachelorThesis | spa |
dc.type.version | info:eu-repo/semantics/acceptedVersion | spa |
dc.subject.proposal | Dengue | spa |
dc.subject.proposal | Epidemiología | spa |
dc.subject.proposal | Hospitalización | spa |
dc.subject.proposal | Población pediátrica | spa |
dc.subject.proposal | Factores sociodemográficos | spa |
dc.subject.proposal | Tuluá | spa |
dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
dc.coverage.city | Tuluá | spa |
dc.type.coarversion | http://purl.org/coar/version/c_ab4af688f83e57aa | spa |
dcterms.audience.professionaldevelopment | Pregrado | spa |
dcterms.audience.professionaldevelopment | Especialización | spa |
dcterms.audience.professionaldevelopment | Maestría | spa |
dc.relation.references | Ministerio de Salud y Protección Social. Dengue. Alerta epidemiológica por dengue en Colombia. 2023. | spa |
dc.relation.references | Ministerio de Salud y Protección Social. Alerta epidemiológica por dengue en Colombia. Alerta epidemiológica por dengue en Colombia.. | spa |
dc.relation.references | World Health Organization. Dengue Guidelines for Diagnosis, Treatment, Prevention and Control: World Health Organization; 2022. | spa |
dc.relation.references | Pan American Health Organization. Dengue in the Americas: Epidemiological Updates. PAHO Epidemiological Bulletin. 2021; 42: p. 1-12. | spa |
dc.relation.references | nstituto Nacional de Salud. INFORME DE EVENTO DENGUE, COLOMBIA 2020.
Boletín Epidemiológico del INS. 2020;: p. 1-20. | spa |
dc.relation.references | Gutierrez-Barbosa HaMMSaZJCaCJV. Dengue Infections in Colombia: Epidemiological Trends of a Hyperendemic Country. Tropical Medicine and Infectious Disease. 2020; 5. | spa |
dc.relation.references | Molineros Gallón LaPGEaRGNaDRC. Seroprevalencia de dengue en municipios con
transmisión hiperendémica y mesoendémica, Valle del Cauca, Colombia. Revista
Colombiana de Salud Pública. 2020; 46: p. e1256. | spa |
dc.relation.references | Hasan SaJSFaAMaAAAaSO. Dengue virus: A global human threat: Review of literature. Journal of International Society of Preventive & Community Dentistry. 2016; 6. | spa |
dc.relation.references | Kamaladasa AaGLaJCaSNaOGSaMGN. Lipopolysaccharide acts synergistically with the dengue virus to induce monocyte production of platelet activating factor and other inflammatory mediators. Antiviral Research. 2016; 133: p. 183-190. | spa |
dc.relation.references | Guzman MGaHE. Dengue. The Lancet. ; 385: p. 453-465. | spa |
dc.relation.references | Macedo GAadAJMGaSHGaCFACadFAMBaSFBdaNRMR. Virological surveillance for
early warning of dengue epidemics in the State of Rio de Janeiro, Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2013; 107. | spa |
dc.relation.references | Gurgel-Gon. The greatest dengue epidemic in Brazil: surveillance, prevention, and control. Revista da Sociedade Brasileira de Medicina Tropical. 2024;: p. e00203--2024. | spa |
dc.relation.references | Halstead SB. Dengue. The Lancet. 2007; 370: p. 1644-1652. | spa |
dc.relation.references | Guzman MGaHE. Dengue. The Lancet. 2015; 385: p. 453-456. | spa |
dc.relation.references | Bhatt Sea. The global distribution and burden of dengue. Nature. 2013; 496: p. 504--507. | spa |
dc.relation.references | Peeling RWea. Diagnostic tests for dengue: an update. The Lancet Infectious Diseases. 2010; 10: p. 160--170. | spa |
dc.relation.references | Guzman MGaKG. Dengue and dengue hemorrhagic fever in the Americas: lessons and challenges. Journal of Clinical Virology. 2003; 27: p. 1--13. | spa |
dc.relation.references | Halstead SB. Pathogenesis of dengue: challenges to molecular biology. Science. 2008; 239: p. 476--481. | spa |
dc.relation.references | Rothman AL. Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms. Nature Reviews Immunology. 2011; 11. | spa |
dc.relation.references | Reiter P. Climate change and mosquito-borne disease. Environmental Health Perspectives. 2010; 109. | spa |
dc.relation.references | Brady OJea. Refining the global spatial limits of dengue virus transmission by evidencebased consensus. PLoS Neglected Tropical Diseases. 2012; 6. | spa |
dc.relation.references | Gubler DJ. Dengue, Urbanization and Globalization: The Unholy Trinity of the 21st Century: Tropical Medicine and Health; 2011. | spa |
dc.relation.references | Padilla JCea. Epidemiology and control of dengue in Colombia. Biomedica. 2011; 31. | spa |
dc.relation.references | Ortiz Dea. Factors associated with dengue transmission in Colombia. International Journal of Infectious Diseases. ; 73. | spa |
dc.relation.references | Alphey Lea. Genetic control of mosquitoes. Annual Review of Entomology. 2010; 55. | spa |
dc.relation.references | Capinera JL. Encyclopedia of Entomology. 2008. | spa |
dc.relation.references | Guy Bea. Evaluation of dengue tetravalent vaccine. Human Vaccines. 2011; 7. | spa |
dc.relation.references | Durbin APaWSS. Next-generation dengue vaccines: novel strategies currently under
development. Viruses. ; 3. | spa |
dc.relation.references | Annan EaTJaZBaRMAJaHU. Direct and indirect effects of age on dengue severity: The mediating role of secondary infection. PLoS neglected tropical diseases. 2023; 17. | spa |
dc.relation.references | Heck KEaPJD. Family structure, socioeconomic status, and access to health care for
children}. Health Services Research. 2002. | spa |
dc.relation.references | Wang LaHWaCYaWQaDXaLQaSC. Intensive care unit nurses' perceptions and practices regarding clinical alarms: A descriptive study. Nursing Open. 2023; 10. | spa |
dc.relation.references | Cho OMaKHaLYWaCI. Clinical alarms in intensive care units: Perceived obstacles of alarm management and alarm fatigue in nurses. Healthcare informatics research. 2016. | spa |
dc.relation.references | Cazzola MaRPaOJaCLaMMG. Asthma and comorbidities: recent advances. Polish archives of internal medicine. 2022; 132. | spa |
dc.relation.references | Barro CaSMaLSaDPaLDK. Simultaneous carriage of multiple serotypes of Group B
Streptococcus: Systematic review and meta-analysis. Vaccine. 2023; 1. | spa |
dc.contributor.orcid | https://orcid.org/0000-0003-4123-6741 | spa |
dc.contributor.orcid | https://orcid.org/0000-0001-6059-9885 | spa |
dcterms.audience.redcol | Grupos de investigación | spa |
dcterms.audience.redcol | Comunidad Cientrífica Colombiana | spa |
dc.subject.keywords | Dengue | spa |
dc.subject.keywords | Epidemiology | spa |
dc.subject.keywords | Hospitalization | spa |
dc.subject.keywords | Pediatric population | spa |
dc.subject.keywords | Sociodemographic factors | spa |
dc.subject.keywords | Tuluá | spa |
dc.description.abstractenglish | Dengue is a viral disease transmitted by mosquitoes of the Aedes genus, representing a
significant global public health concern due to its high morbidity burden and the substantial
healthcare and social costs associated with its management (1,2). In Colombia, the incidence of
dengue has shown a steady increase in recent decades, driven by the simultaneous circulation of
multiple serotypes and environmental conditions favorable to vector proliferation (2).
This systematic review aims to analyze the available scientific evidence on the
sociodemographic, clinical, and epidemiological factors associated with dengue-related
hospitalizations in school-aged pediatric populations. The review seeks to identify common
patterns and key determinants influencing clinical severity and the need for inpatient care, thereby
contributing to clinical decision-making and the development of public health policies.
Variables such as age, sex, socioeconomic status, epidemiological background, clinical
manifestations, and laboratory findings are examined to characterize the risk factors associated
with increased severity of dengue in children aged 6 to 17 years.
The findings of this review are expected to inform the design of health promotion and
disease prevention strategies aimed at reducing hospital admissions and preventing severe
complications from dengue, particularly in vulnerable pediatric populations. Additionally, the
review aims to support the strengthening of public health policies through the identification of
critical determinants that can guide the implementation of effective interventions, optimize
resource allocation, and improve vector control and timely patient care. | spa |
dc.contributor.cvlac | https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001429373 | spa |
dc.contributor.cvlac | https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000146508 | spa |